Preprocessing

QC quality

pp.calculate_global_moran(adata[, ...])	Compute global Moran's I for each gene and return a new AnnData object containing only genes with significant spatial autocorrelation (p-value < alpha).
pp.preprogress_adata(adata_omics1, adata_omics2)	Preprocess two spatial omics AnnData objects by removing spots/cells with no cross-omics spatial neighbors.

Downsampling

pp.downsampling(adata, resolution[, method, ...])

Downsample a spatial omics dataset by binning spots/cells into a regular grid.

Patch

pp.extract_spatial_region(adata, minx, miny, ...)	Extract a spatial region from an AnnData object based on spatial coordinates.
pp.clipping_patch(adata_omics1, adata_omics2)	Divide the overlapping spatial region of two spatial omics into a grid of patches.